Ernest C. Madu, MD, FACC

Dr. Ernest Madu is an internationally recognized cardiologist and clinical investigator. He is an expert in healthcare innovation and health systems transformation. He has lectured extensively around the world. His research works have been presented worldwide, published and cited in leading journals of cardiovascular medicine

Title Senior Consultant Cardiolgist and Chairman, Heart Institute of the Caribbean and HIC Heart Hospital
Department and Services Cardiovascular Medicine
Areas of Expertise
  • Cardiovascular Imaging
  • Echocardiography
  • Nuclear Cardiology
  • Valvular Heart Disease
  • Ischemic Heart Disease
  • Critical Care Cardiology
Seeing Patients in:
  • Heart Institution of the Caribbean & HIC Heart Hospital, Kingston
  • Andrews Memorial Medical Centre, Kinston
  • HIC Heart Station,Spanish Town
  • Heart Institution of the Caribbean, Mandeville
  • Heart Institution of the Caribbean, Ocho Rios

Honors and Awards

Invited Speaker, TED Global 2007,
Leadership in Diversity Award, Association of Black Cardiologists (ABC), 2007,
Very Talented Person Award, VTP.org, 2009,
Global Best Award of Excellence in Medicine and Public Health, Nigeria (Ola Ndi Igbo), 2013,
Named among “30 Most Influential in Public Health, Masters in Public Health, 2013,
Civic Leadership Award, American Chamber of Commerce, 2015,
Elected Fellow of The International Academy of Cardiovascular Sciences – 2015,
Global Health Champion Award, University of Pennsylvania, 2016,
Distinguished Cardiologist Award (International Service), American College of Cardiology, 2017,
Named among 100 Most Influential People in Healthcare, GrupoMidia, 2017.

Published Research

Mezue K, Isiguzo G, Madu C, Nwuruku G, Rangaswami J, Baugh D, Madu E. Nocturnal Non-dipping Blood Pressure Profile in Black Normotensives Is Associated with Cardiac Target Organ Damage. Ethn Dis. 2016 Jul 21;26(3):279-84. doi: 10.18865/ed.26.3.279. PubMed PMID: 27440966; PubMed Central PMCID: PMC4948793.
Free full textCited in PMCRelated citations

Potu C, Tulloch-Reid E, Baugh D, Madu E. Left ventricular thrombus in patients with acute myocardial infarction:Case report and Caribbean focused update. Australas Med J. 2012;5(3):178-83. doi: 10.4066/AMJ.20121103. Epub 2012 Mar 31. PubMed PMID: 22952564; PubMed Central PMCID: PMC3422718.
Free full textCited in PMCRelated citations

Madu EC, Potu C, Baugh D, Tulloch-Reid E. Myocardial Contrast Echocardiography in the Evaluation of Hypertensive Heart Disease. Cardiol Res. 2011 Dec;2(6):259-268. doi: 10.4021/cr93w. Epub 2011 Nov 20. Review. PubMed PMID: 28352393; PubMed Central PMCID: PMC5358253.
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Madu EC, Tulloch-Reid MK, Baugh DS, Tulloch-Reid E, Potu C. Clinical utility of transoesophageal echocardiography in low resource environments: the Jamaican experience. West Indian Med J. 2011 Dec;60(6):653-7. PubMed PMID: 22512223.
Related citations

Madu EC, Tulloch-Reid E, Edwards P, Baugh DS, Kong BW. Developing sustainable cardiovascular care for low-resource nations. J Am Coll Cardiol. 2009 Sep 8;54(11):1038-9; author reply 1039. doi: 10.1016/j.jacc.2008.07.077. PubMed PMID: 19729124.
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Khoo MS, Li J, Singh MV, Yang Y, Kannankeril P, Wu Y, Grueter CE, Guan X, Oddis CV, Zhang R, Mendes L, Ni G, Madu EC, Yang J, Bass M, Gomez RJ, Wadzinski BE, Olson EN, Colbran RJ, Anderson ME. Death, cardiac dysfunction, and arrhythmias are increased by calmodulin kinase II in calcineurin cardiomyopathy. Circulation. 2006 Sep 26;114(13):1352-9. Epub 2006 Sep 18. PubMed PMID: 16982937.
Cited in PMCRelated citations

Zhang R, Khoo MS, Wu Y, Yang Y, Grueter CE, Ni G, Price EE Jr, Thiel W, Guatimosim S, Song LS, Madu EC, Shah AN, Vishnivetskaya TA, Atkinson JB, Gurevich VV, Salama G, Lederer WJ, Colbran RJ, Anderson ME. Calmodulin kinase II inhibition protects against structural heart disease. Nat Med. 2005 Apr;11(4):409-17. Epub 2005 Mar 27. PubMed PMID: 15793582.
Cited in PMCRelated citations

Lemogoum D, Van Bortel L, Najem B, Dzudie A, Teutcha C, Madu E, Leeman M, Degaute JP, van de Borne P. Arterial stiffness and wave reflections in patients with sickle cell disease. Hypertension. 2004 Dec;44(6):924-9. Epub 2004 Nov 8. PubMed PMID: 15534075.
Cited in PMCRelated citations

Rottman JN, Ni G, Khoo M, Wang Z, Zhang W, Anderson ME, Madu EC. Temporal changes in ventricular function assessed echocardiographically in conscious and anesthetized mice. J Am Soc Echocardiogr. 2003 Nov;16(11):1150-7. PubMed PMID: 14608286.
Cited in PMCRelated citations

Madu EC, Richardson KD, Ozigbo OH, Baugh DS. Improving cardiovascular disease prevention and management in Africa: issues to consider for the 21st century. Ethn Dis. 2003 Summer;13(2 Suppl 2):S71-6. PubMed PMID: 13677417.
Cited in PMCRelated citations

Dhala A, Underwood D, Leman R, Madu E, Baugh D, Ozawa Y, Kasamaki Y, Xue Q, Reddy S; Multicenter PHi-Res Study.. Signal-averaged P-wave analysis of normal controls and patients with paroxysmal atrial fibrillation: a study in gender differences, age dependence, and reproducibility. Clin Cardiol. 2002 Nov;25(11):525-31. PubMed PMID: 12430783.
Cited in PMCRelated citations

Madu EC, Baugh DS, D’Cruz IA, Johns C. Left ventricular papillary muscle morphology and function in left ventricular hypertrophy and left ventricular dysfunction. Med Sci Monit. 2001 Nov-Dec;7(6):1212-8. PubMed PMID: 11687732.
Cited in PMCRelated citations

Madu EC, Baugh DS, Johns C, D’Cruz IA. Papillary muscle contribution to ventricular ejection in normal and hypertrophic ventricles: a transesophageal echocardiographic study. Echocardiography. 2001 Nov;18(8):633-8. PubMed PMID: 11801204.
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Madu EC, Baugh DS, Gbadebo TD, Dhala A, Cardoso S; Phi-Res Multi-Study Group.. Effect of ethnicity and hypertension on atrial conduction: evaluation with high-resolution P-wave signal averaging. Clin Cardiol. 2001 Sep;24(9):597-602. PubMed PMID: 11558841.
Cited in PMCRelated citations

Madu EC, Hanumanthu SK, Kim C, Prudoff A. Recurrent ischemia resulting from left internal mammary artery-to-pulmonary artery fistula. Angiology. 2001 Mar;52(3):185-8. PubMed PMID: 11269781.
Cited in PMCRelated citations

Madu EC. Transesophageal dobutamine stress echocardiography in the evaluation of myocardial ischemia in morbidly obese subjects. Chest. 2000 Mar;117(3):657-61. PubMed PMID: 10712988.
Cited in PMCRelated citations

Madu EC, D’Cruz IA, Wall B, Mansour N, Shearin S. Transesophageal echocardiographic spectrum of calcific mitral abnormalities in patients with end-stage renal disease. Echocardiography. 2000 Jan;17(1):29-35. PubMed PMID: 10978956.
Cited in PMCRelated citations

Madu EC, Shala B, Baugh D. Crack-cocaine-associated aortic dissection in early pregnancy–a case report. Angiology. 1999 Feb;50(2):163-8. Review. PubMed PMID: 10063949.
Cited in PMCRelated citations

Dhala A, Underwood D, Madu E, Angel J. Sex-specific differences in the P wave signal-averaged ECG. Multicenter P HiRes Study. J Electrocardiol. 1998;30 Suppl:34-5. PubMed PMID: 9535478.
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Wolford DC, Jost CM, Madu EC, Walker W, Ramanatian KB. Role of transesophageal echocardiography in the clinical management of a patients with a giant coronary artery aneurysm. Clin Cardiol. 1997 Jun;20(6):573-5. PubMed PMID: 9181270.
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Madu EC, Brown R, Geraci SA. Dynamic left ventricular outflow tract obstruction in critically ill patients: role of transesophageal echocardiography in therapeutic decision making. Cardiology. 1997 May-Jun;88(3):292-5. PubMed PMID: 9129852.
Cited in PMCRelated citations

Rashed HM, Leventhal G, Madu EC, Reddy R, Cardoso S. Reproducibility of exercise-induced modulation of cardiovascular responses to cold stress. Clin Auton Res. 1997 Apr;7(2):93-6. PubMed PMID: 9174657.
Cited in PMCRelated citations

Madu EC, D’Cruz IA. The vital role of papillary muscles in mitral and ventricular function: echocardiographic insights. Clin Cardiol. 1997 Feb;20(2):93-8. Review. PubMed PMID: 9034636.
Cited in PMCRelated citations

Whitby S, Madu EC, Bronze MS. Case report: Candida zeylanoides infective endocarditis complicating infection with the human immunodeficiency virus. Am J Med Sci. 1996 Sep;312(3):138-9. PubMed PMID: 8783683.
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Madu EC, Reddy RC, Madu AN, Anyaogu C, Harris T, Fraker TD Jr. Review: the effects of antihypertensive agents on serum lipids. Am J Med Sci. 1996 Aug;312(2):76-84. Review. PubMed PMID: 8701970.
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American College of Cardiology
Association of Black Cardiologists
International Academy of Cardiovascular Sciences